Nucleic Acid Delivery Devices for HIV Vaccines


The Vaccine Research Program, Division of AIDS, NIAID together with the Global HIV Vaccine Enterprise organized a workshop to discuss nucleic acid delivery technologies important for research and development of preventive HIV vaccines. The workshop was held at the National Institutes of Health on May 21, 2015.

Chaired by Dr. Bruce G. Weniger, the workshop reviewed the landscape of past, current and future technologies for delivering nucleic acid (NA) antigens into target tissues of animal models and humans, with a focus on the prevention and treatment of HIV/AIDS. Participants learned from the results and experience of representative clinical trials of nucleic acid vaccines using a variety of delivery devices, as well as the diverse methods studied in animal models and in the lab to improve upon the performance, and/or avoid the drawbacks of conventional needle-syringe delivery.

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