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The Immune Space: A Concept and Template for Rationalizing Vaccine Development

The Enterprise and partners published a paper on "The Immune Space: A Concept and Template for Rationalizing Vaccine Development".  The “immune space template” proposed provides a standardized approach by which the quality, level, and durability of immune responses elicited in early human trials by a candidate vaccine can be described. The immune response profile will demonstrate if and how the candidate is unique relative to other candidates, especially those that have preceded it into efficacy testing and, thus, what new information concerning potential immune correlates could be learned from an efficacy trial.

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